产品货号：
Z37449
中文名称：
Hu Nectin-1/PVRL1/NECTIN1 Purified抗体
英文名称：
Anti-Hu Nectin-1/PVRL1/NECTIN1 Purified Antibody (Clone#R1.302)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu Nectin-1/PVRL1/NECTIN1 Purified Antibody (Clone#R1.302) |
| 指标别名 | CD111;CLPED1;ED4;Herpes virus entry mediator C;Herpesvirus entry mediator C;Herpesvirus Ig like receptor;HIgR;HVEC;nectin 1;Nectin-1;OFC7;PRR;PRR1;PVRL1;PVRR;PVRR1;SK 12 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IP,WB,IHC,ICC |
| 基因名称 | NECTIN1 |
| 克隆号 | R1.302 |
| 抗体来源 | Mouse |
| 免疫原 | NIH/3T3 cells transfected with human CD111.The mouse monoclonal antibody R1.302 recognizes an extracellular epitope on CD111 (also known as Nectin 1),a 75kDa type I transmembrane glycoprotein broadly expressed on endothelial cells,epithelial cells,neuronal cells,megakaryocytes,and CD34-positive stem cells. |
| 计算分子量 | 57kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD111,also known as nectin-1,is a calcium-independent cell-cell adhesion transmembrane glycoprotein involved in organization of adherens junctions and tight junctions in epithelial and endothelial cells.It also serves as a target molecule for entry of herpes simplex virus (HSV-1,HSV-2) and pseudorabies virus (PRV) into epithelial and neuronal cells.CD111 is connected with actin cytoskeleton through afadin.Mutations in the gene for CD111 cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P).Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. |
| Uniprot ID | Q15223 |
| 基因名全称 | Nectin cell adhesion molecule 1 |
| 蛋白名全称 | Nectin-1 |
| 推荐稀释比 | Flow cytometry:1～4μg/mL. |
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